Mental depression in patients with tuberculosis in Yaounde, Cameroon
DOI:
https://doi.org/10.5281/zenodo.20562662Keywords:
Depression, tuberculosis, Sub-Saharan AfricaAbstract
Introduction: The aim of this study was to compare the prevalence of the mental depression (MD) in adults with active TB and those who had never had TB and to investigate the associated factors of MD in patients with TB.
Methods: This was a case-control study including 298 adults with TB aged 18 years and above (TB group) and 298 controls (control group). The cases were TB patients hospitalized at Yaoundé Jamot Hospital from January to December 2012. The controls were subjects who had never had active TB and were selected from those who participated in a respiratory health survey (ESR) in Yaoundé from December 2013 to April 2014 and included using 3-level stratified sampling method. Controls were matched by sex and age (± 2 years) by random selection among adult subjects included in the ESR. MD was defined by a Patient Health Questionnaire 9 (PHQ-9) score ≥ 10. Logistic regression was used to investigate the factors associated with MD.
Results: In both groups, 189 subjects (63.4%) were men and the mean age (standard deviation) was 36.4 (12) years in the TB group and 36.1 (12.5) years in the control group (p = 0.567). The prevalence of MD in the TB group was 30.9% versus 7.7% in the control group (p <0.001). In multivariate analysis, active TB was a risk factor for MD with an adjusted odds ratio (AOR) of 14.93 (95% CI: 4.30-51.93). In the TB group, the independent associated factors to MD were female gender [ORA (95% CI): 1.85 (1.08-3.17)] and pulmonary TB [3.13 (1.50 -6, 52)].
Conclusion: TB is a risk factor for mental depression in Yaoundé. It is important to look for mental depression in subjects with TB, especially in high-risk groups in order to optimize the overall management of these patients.
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Copyright (c) 2018 Adamou Dodo Balkissou, Pefura-Yone Eric Walter, Kamga Olen Jean-Pierre, Efe-de-Melingui Nelly Rachel, Afane-Ze Emmanuel (Auteur·e)
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